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Transcriptional activation by Myc is under negative control by the transcription factor AP-2.

The Myc protein binds to and transactivates the expression of genes via E-box elements containing a central CAC(G/A)TG sequence. The transcriptional activation function of Myc is required for its ability to induce cell cycle progression, cellular transformation and apoptosis. Here we show that trans...

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Detalhes bibliográficos
Main Authors: Gaubatz, S, Imhof, A, Dosch, R, Werner, O, Mitchell, P, Buettner, R, Eilers, M
Formato: Artigo
Idioma:Inglês
Publicado em: 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC398238/
https://ncbi.nlm.nih.gov/pubmed/7729426
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