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Transcriptional activation by Myc is under negative control by the transcription factor AP-2.

The Myc protein binds to and transactivates the expression of genes via E-box elements containing a central CAC(G/A)TG sequence. The transcriptional activation function of Myc is required for its ability to induce cell cycle progression, cellular transformation and apoptosis. Here we show that trans...

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Detalles Bibliográficos
Publicado en:EMBO J
Principais autores: Gaubatz, S, Imhof, A, Dosch, R, Werner, O, Mitchell, P, Buettner, R, Eilers, M
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 1995
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398238/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7729426/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07137.x
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