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Tissue mechanics modulate microRNA-dependent PTEN expression to regulate malignant progression

Tissue mechanics regulate development and homeostasis and are consistently modified in tumor progression. Nevertheless, the fundamental molecular mechanisms through which altered mechanics regulate tissue behavior and the clinical relevance of these changes remain unclear. We demonstrate that increa...

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מידע ביבליוגרפי
Main Authors: Mouw, Janna K, Yui, Yoshihiro, Damiano, Laura, Bainer, Russell O, Lakins, Johnathan N, Acerbi, Irene, Ou, Guanqing, Wijekoon, Amanda C, Levental, Kandice R, Gilbert, Penney M, Chen, Yunn-Yi, Weaver, Valerie M
פורמט: Artigo
שפה:Inglês
יצא לאור: 2014
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981899/
https://ncbi.nlm.nih.gov/pubmed/24633304
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3497
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