Elevated Levels of Mitochondrion-associated Autophagy Inhibitor LRPPRC Are Associated with Poor Prognosis of Human Patients with Prostate Cancer

BACKGROUND: Autophagy has recently been found to play important roles in tumorigenesis and LRPPRC has been identified as an inhibitor that suppresses autophagy and mitophagy and maintains mitochondrial activity. We hypothesized that LRPPRC levels can be used as a biomarker for diagnosis and prognosi...

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Hauptverfasser: Jiang, Xianhan, Li, Xun, Huang, Hai, Jiang, Funeng, Lin, Zhuoyuan, He, Huichan, Chen, Yanru, Yue, Fei, Zou, Jing, He, Yongzhong, You, Pan, Wang, Wenwei, Yang, Weiqing, Zhao, Haibo, Lai, Yiming, Wang, Fen, Zhong, Weide, Liu, Leyuan
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981875/
https://ncbi.nlm.nih.gov/pubmed/24390809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.28551
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