Regulation of Raf-1 kinase activity by the 14-3-3 family of proteins.

We have identified the beta (beta) isoform of the 14-3-3 family of proteins as an activator of the Raf-1 protein kinase. 14-3-3 was isolated in a yeast two-hybrid screen for Raf-1 kinase domain binding proteins. Purified bovine brain 14-3-3 interacted specifically with both c-Raf-1 and the isolated...

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Autores principales: Li, S, Janosch, P, Tanji, M, Rosenfeld, G C, Waymire, J C, Mischak, H, Kolch, W, Sedivy, J M
Formato: Artigo
Lenguaje:Inglês
Publicado: 1995
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC398132/
https://ncbi.nlm.nih.gov/pubmed/7882972
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