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Random activation of a transgene under the control of a hybrid hCD2 locus control region/Ig enhancer regulatory element.

Locus control regions such as those of human CD2 and beta-globin differ from classical enhancers in that, whereas the former confer high level, copy-dependent, position-independent expression to linked genes in transgenic mice, the latter do not, expression levels being dependent on the site of inte...

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Detalhes bibliográficos
Publicado no:EMBO J
Main Authors: Elliott, J I, Festenstein, R, Tolaini, M, Kioussis, D
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 1995
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC398116/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7859745/
https://ncbi.nlm.nih.govhttps://doi.org/10.1002/j.1460-2075.1995.tb07033.x
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