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Sulforaphane synergistically enhances the cytotoxicity of arsenic trioxide in multiple myeloma cells via stress-mediated pathways

Persistent paraprotein production in plasma cells necessitates a highly developed rough endoplasmic reticulum (ER) that is unusually susceptible to perturbations in protein synthesis. This biology is believed to account for the exquisite sensitivity of multiple myeloma (MM) to the proteasomal inhibi...

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Bibliografiske detaljer
Main Authors: DOUDICAN, NICOLE A., WEN, SHIH YA, MAZUMDER, AMITABHA, ORLOW, SETH J.
Format: Artigo
Sprog:Inglês
Udgivet: D.A. Spandidos 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981004/
https://ncbi.nlm.nih.gov/pubmed/22922937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2012.1977
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