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Antagonistic Effect of Small Molecule Inhibitors of Wnt/β-catenin in Multiple Myeloma

BACKGROUND: Development and progression of multiple myeloma is dependent on the bone marrow (BM) microenvironment, and within the BM, a number of factors are secreted, including the Wnt ligands. Bone marrow stromal cells (BMSC) secrete Wnt ligands that activate Wnt signaling in multiple myeloma. The...

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Bibliografski detalji
Glavni autori: Narayanan, Bhagavathi A., Doudican, Nicole A., Park, Jeesun, Xu, Dazhong, Narayanan, Narayanan K., Dasgupta, Ramanuj, Mazumder, Amitabha
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983472/
https://ncbi.nlm.nih.gov/pubmed/23155232
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