Antagonistic Effect of Small Molecule Inhibitors of Wnt/β-catenin in Multiple Myeloma

BACKGROUND: Development and progression of multiple myeloma is dependent on the bone marrow (BM) microenvironment, and within the BM, a number of factors are secreted, including the Wnt ligands. Bone marrow stromal cells (BMSC) secrete Wnt ligands that activate Wnt signaling in multiple myeloma. The...

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Detalhes bibliográficos
Main Authors: Narayanan, Bhagavathi A., Doudican, Nicole A., Park, Jeesun, Xu, Dazhong, Narayanan, Narayanan K., Dasgupta, Ramanuj, Mazumder, Amitabha
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3983472/
https://ncbi.nlm.nih.gov/pubmed/23155232
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