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Sulforaphane synergistically enhances the cytotoxicity of arsenic trioxide in multiple myeloma cells via stress-mediated pathways

Persistent paraprotein production in plasma cells necessitates a highly developed rough endoplasmic reticulum (ER) that is unusually susceptible to perturbations in protein synthesis. This biology is believed to account for the exquisite sensitivity of multiple myeloma (MM) to the proteasomal inhibi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: DOUDICAN, NICOLE A., WEN, SHIH YA, MAZUMDER, AMITABHA, ORLOW, SETH J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981004/
https://ncbi.nlm.nih.gov/pubmed/22922937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2012.1977
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