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Sulforaphane synergistically enhances the cytotoxicity of arsenic trioxide in multiple myeloma cells via stress-mediated pathways

Persistent paraprotein production in plasma cells necessitates a highly developed rough endoplasmic reticulum (ER) that is unusually susceptible to perturbations in protein synthesis. This biology is believed to account for the exquisite sensitivity of multiple myeloma (MM) to the proteasomal inhibi...

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Detalhes bibliográficos
Main Authors: DOUDICAN, NICOLE A., WEN, SHIH YA, MAZUMDER, AMITABHA, ORLOW, SETH J.
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3981004/
https://ncbi.nlm.nih.gov/pubmed/22922937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2012.1977
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