Siglec-F Inhibition Reduces Esophageal Eosinophilia and Angiogenesis in a Mouse Model of Eosinophilic Esophagitis

OBJECTIVES: Eosinophilic esophagitis (EoE) is a disorder characterized histologically by tissue eosinophilia. Sialic acid–binding immunoglobulin-like lectin (Siglec-F) is a receptor highly expressed on mouse eosinophils and mediates eosinophilic apoptosis. We investigated whether administration of a...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Rubinstein, Eitan, Cho, Jae Youn, Rosenthal, Peter, Chao, James, Miller, Marina, Pham, Alexa, Aceves, Seema S., Varki, Ajit, Broide, David H.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2011
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980963/
https://ncbi.nlm.nih.gov/pubmed/21970996
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/MPG.0b013e3182182ff8
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