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Mice deficient for prion protein exhibit normal neuronal excitability and synaptic transmission in the hippocampus.

We recorded in the CA1 region from hippocampal slices of prion protein (PrP) gene knockout mice to investigate whether the loss of the normal form of prion protein (PrPC) affects neuronal excitability as well as synaptic transmission in the central nervous system. No deficit in synaptic inhibition w...

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Detalhes bibliográficos
Main Authors: Lledo, P M, Tremblay, P, DeArmond, S J, Prusiner, S B, Nicoll, R A
Formato: Artigo
Idioma:Inglês
Publicado em: 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC39809/
https://ncbi.nlm.nih.gov/pubmed/8637886
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