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Molecular Pathways: Emerging Roles of Mammalian Sirtuin SIRT7 in Cancer

SIRT7 belongs to the Sirtuin family of NAD-dependent enzymes, whose members play diverse roles in aging, metabolism, and disease biology. Increased SIRT7 expression is observed in human cancers, and growing evidence suggests important SIRT7 functions in fundamental cellular programs that impact on o...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: Paredes, Silvana, Villanova, Lidia, Chua, Katrin F.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980586/
https://ncbi.nlm.nih.gov/pubmed/24536059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-13-1547
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