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Sirtuins: New Roles for Sirtuins in Aging and Disease
Sirtuins are NAD+-dependent enzymes related to yeast silent information regulator-2, a histone deacetylase that prevents premature aging through chromatin silencing. Mammalian sirtuins, SIRT1-SIRT7, have key functions that protect against diverse aging-related pathologic states, from cancer to metab...
में बचाया:
| में प्रकाशित: | Innov Aging |
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| मुख्य लेखक: | |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Oxford University Press
2020
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7743872/ https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igaa057.2650 |
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