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Sirtuins: New Roles for Sirtuins in Aging and Disease

Sirtuins are NAD+-dependent enzymes related to yeast silent information regulator-2, a histone deacetylase that prevents premature aging through chromatin silencing. Mammalian sirtuins, SIRT1-SIRT7, have key functions that protect against diverse aging-related pathologic states, from cancer to metab...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Innov Aging
Prif Awdur: Chua, Katrin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2020
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC7743872/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/geroni/igaa057.2650
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