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Intravenous ascorbate improves spatial memory in middle-aged APP/PSEN1 and wild type mice
The present study investigated the effects of a single intravenous (i.v.) dose of Vitamin C (ascorbate, ASC) on spatial memory in APP/PSEN1 mice, an Alzheimer's disease model. First, we confirmed the uptake time course in ASC-depleted gulo (−/−) mice, which cannot synthesize ASC. Differential t...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3980584/ https://ncbi.nlm.nih.gov/pubmed/24508240 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2014.01.044 |
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