Type 5 Adenylyl Cyclase Increases Oxidative Stress by Transcriptional Regulation of MnSOD via the SIRT1/FoxO3a Pathway

BACKGROUND: For reasons that remain unclear, whether type 5 AC (AC5), one of two major AC isoforms in heart, is protective or deleterious in response to cardiac stress is controversial. To reconcile this controversy we examined the cardiomyopathy induced by chronic isoproterenol (ISO) in AC5 transge...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Lai, Lo, Yan, Lin, Gao, Shumin, Hu, Che-Lin, Ge, Hui, Davidow, Amy, Park, Misun, Bravo, Claudio, Iwatsubo, Kousaku, Ishikawa, Yoshihiro, Auwerx, Johan, Sinclair, David A., Vatner, Stephen F., Vatner, Dorothy E.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2013
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980473/
https://ncbi.nlm.nih.gov/pubmed/23536361
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.112.001212
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller