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Comparison of multiple adjuvants on the stability and immunogenicity of a clade C HIV-1 gp140 trimer

Immunogens based on the human immunodeficiency virus type-1 (HIV-1) Envelope (Env) glycoprotein have to date failed to elicit potent and broadly neutralizing antibodies against diverse HIV-1 strains. An understudied area in the development of HIV-1 Env-based vaccines is the impact of various adjuvan...

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Detalhes bibliográficos
Main Authors: Nkolola, Joseph P., Cheung, Ann, Perry, James R., Carter, Darrick, Reed, Steve, Schuitemaker, Hanneke, Pau, Maria Grazia, Seaman, Michael S., Chen, Bing, Barouch, Dan H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3980048/
https://ncbi.nlm.nih.gov/pubmed/24556505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.02.001
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