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De novo fatty acid synthesis at the mitotic exit is required to complete cellular division

Although the regulation of the cell cycle has been extensively studied, much less is known about its coordination with the cellular metabolism. Using mass spectrometry we found that lysophospholipid levels decreased drastically from G(2)/M to G(1) phase, while de novo phosphatidylcholine synthesis,...

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Bibliographic Details
Main Authors: Scaglia, Natalia, Tyekucheva, Svitlana, Zadra, Giorgia, Photopoulos, Cornelia, Loda, Massimo
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979921/
https://ncbi.nlm.nih.gov/pubmed/24418822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.27767
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