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CD8(+) Regulatory T Cells, and Not CD4(+) T Cells, Dominate Suppressive Phenotype and Function after In Vitro Live Mycobacterium bovis-BCG Activation of Human Cells
Mycobacterium bovis bacillus Calmette-Guérin (M. bovis BCG), the only currently available vaccine against tuberculosis, has been reported to induce regulatory T cells in humans. The activity of regulatory T cells may not only dampen immunogenicity and protective efficacy of tuberculosis-vaccines, bu...
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Formato: | Artigo |
Idioma: | Inglês |
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Public Library of Science
2014
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3979753/ https://ncbi.nlm.nih.gov/pubmed/24714620 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0094192 |
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