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T-Cell Recognition of the HspX Protein of Mycobacterium tuberculosis Correlates with Latent M. tuberculosis Infection but Not with M. bovis BCG Vaccination

During stationary growth or in vitro conditions mimicking relevant aspects of latency, the HspX protein (Rv2031c) is specifically upregulated by Mycobacterium tuberculosis. In this study we compared T-cell responses against HspX and the secreted M. tuberculosis protein Ag85B (Rv1886c) in tuberculosi...

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Détails bibliographiques
Auteurs principaux: Geluk, Annemieke, Lin, May Young, van Meijgaarden, Krista E., Leyten, Eliane M. S., Franken, Kees L. M. C., Ottenhoff, Tom H. M., Klein, Michèl R.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2007
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932904/
https://ncbi.nlm.nih.gov/pubmed/17387166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01990-06
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