T-Cell Recognition of the HspX Protein of Mycobacterium tuberculosis Correlates with Latent M. tuberculosis Infection but Not with M. bovis BCG Vaccination

During stationary growth or in vitro conditions mimicking relevant aspects of latency, the HspX protein (Rv2031c) is specifically upregulated by Mycobacterium tuberculosis. In this study we compared T-cell responses against HspX and the secreted M. tuberculosis protein Ag85B (Rv1886c) in tuberculosi...

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Detalhes bibliográficos
Main Authors: Geluk, Annemieke, Lin, May Young, van Meijgaarden, Krista E., Leyten, Eliane M. S., Franken, Kees L. M. C., Ottenhoff, Tom H. M., Klein, Michèl R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2007
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932904/
https://ncbi.nlm.nih.gov/pubmed/17387166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01990-06
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