T-Cell Recognition of the HspX Protein of Mycobacterium tuberculosis Correlates with Latent M. tuberculosis Infection but Not with M. bovis BCG Vaccination

During stationary growth or in vitro conditions mimicking relevant aspects of latency, the HspX protein (Rv2031c) is specifically upregulated by Mycobacterium tuberculosis. In this study we compared T-cell responses against HspX and the secreted M. tuberculosis protein Ag85B (Rv1886c) in tuberculosi...

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Bibliographische Detailangaben
Hauptverfasser: Geluk, Annemieke, Lin, May Young, van Meijgaarden, Krista E., Leyten, Eliane M. S., Franken, Kees L. M. C., Ottenhoff, Tom H. M., Klein, Michèl R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2007
Schlagworte:
Host Response and Inflammation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1932904/
https://ncbi.nlm.nih.gov/pubmed/17387166
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01990-06
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