Detailed characterization of human Mycobacterium tuberculosis specific HLA-E restricted CD8(+) T cells

HLA-E presented antigens are interesting targets for vaccination given HLA-Es’ essentially monomorphic nature. We have shown previously that Mycobacterium tuberculosis (Mtb) peptides are presented by HLA-E to CD8(+) effector T cells, but the precise phenotype and functional capacity of these cells r...

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Publicado en:Eur J Immunol
Autores principales: Prezzemolo, Teresa, van Meijgaarden, Krista E., Franken, Kees L.M.C., Caccamo, Nadia, Dieli, Francesco, Ottenhoff, Tom H.M., Joosten, Simone A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2017
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6266868/
https://ncbi.nlm.nih.gov/pubmed/29124751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201747184
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