Interleukin 2 (IL-2) augments transcription of the IL-2 receptor gene.

We demonstrate that purified interleukin 2 (IL-2) can directly upregulate IL-2 receptor expression on phytohemagglutinin-activated T lymphocytes maintained in culture until IL-2 receptor expression had markedly declined. The IL-2-induced increase in IL-2 receptor number is maximal within 12 hr, requ...

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Détails bibliographiques
Auteurs principaux: Depper, J M, Leonard, W J, Drogula, C, Krönke, M, Waldmann, T A, Greene, W C
Format: Artigo
Langue:Inglês
Publié: 1985
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC397970/
https://ncbi.nlm.nih.gov/pubmed/2987968
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