Interleukin 2 (IL-2) augments transcription of the IL-2 receptor gene.

We demonstrate that purified interleukin 2 (IL-2) can directly upregulate IL-2 receptor expression on phytohemagglutinin-activated T lymphocytes maintained in culture until IL-2 receptor expression had markedly declined. The IL-2-induced increase in IL-2 receptor number is maximal within 12 hr, requ...

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Veröffentlicht in:	Proc Natl Acad Sci U S A
Hauptverfasser:	Depper, J M, Leonard, W J, Drogula, C, Krönke, M, Waldmann, T A, Greene, W C
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	National Academy of Sciences 1985
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC397970/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2987968/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.82.12.4230
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