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Cyclosporin A inhibits T-cell growth factor gene expression at the level of mRNA transcription.

Cyclosporin A (CsA) is a potent immunosuppressive agent, now gaining wide application in human organ transplantation. The immunosuppressive activity of CsA is at least in part due to inhibition of lymphokine production by activated T lymphocytes. Specifically, inhibition of T-cell growth factor (TCG...

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Autors principals: Krönke, M, Leonard, W J, Depper, J M, Arya, S K, Wong-Staal, F, Gallo, R C, Waldmann, T A, Greene, W C
Format: Artigo
Idioma:Inglês
Publicat: 1984
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC391668/
https://ncbi.nlm.nih.gov/pubmed/6332315
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