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Isolating Nuclei from Cultured Cells for Patch-Clamp Electrophysiology of Intracellular Ca(2+) Channels

Nuclear patch-clamp experiments can be performed with intact nuclei or with nuclei from which the outer nuclear membrane has been removed. This protocol presents procedures for harvesting different types of cultured cells, isolating nuclei, and exposing the inner nuclear membrane by agitating in the...

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Autors principals: Mak, Don-On Daniel, Vais, Horia, Cheung, King-Ho, Foskett, J. Kevin
Format: Artigo
Idioma:Inglês
Publicat: 2013
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979423/
https://ncbi.nlm.nih.gov/pubmed/24003193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/pdb.prot073056
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