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Estradiol Stimulates Glucose Metabolism via 6-Phosphofructo-2-kinase (PFKFB3)
Estradiol (E2) administered to estrogen receptor-positive (ER(+)) breast cancer patients stimulates glucose uptake by tumors. Importantly, this E2-induced metabolic flare is predictive of the clinical effectiveness of anti-estrogens and, as a result, downstream metabolic regulators of E2 are expecte...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3979387/ https://ncbi.nlm.nih.gov/pubmed/24515104 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.529990 |
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