Estradiol Stimulates Glucose Metabolism via 6-Phosphofructo-2-kinase (PFKFB3)

Estradiol (E2) administered to estrogen receptor-positive (ER(+)) breast cancer patients stimulates glucose uptake by tumors. Importantly, this E2-induced metabolic flare is predictive of the clinical effectiveness of anti-estrogens and, as a result, downstream metabolic regulators of E2 are expecte...

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Main Authors: Imbert-Fernandez, Yoannis, Clem, Brian F., O'Neal, Julie, Kerr, Daniel A., Spaulding, Robert, Lanceta, Lilibeth, Clem, Amy L., Telang, Sucheta, Chesney, Jason
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Metabolism
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979387/
https://ncbi.nlm.nih.gov/pubmed/24515104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.529990
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