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Inhibition of 6-phosphofructo-2-kinase (PFKFB3) induces autophagy as a survival mechanism
BACKGROUND: Unlike glycolytic enzymes that directly catabolize glucose to pyruvate, the family of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatases (PFKFBs) control the conversion of fructose-6-phosphate to and from fructose-2,6-bisphosphate, a key regulator of the glycolytic enzyme phosphofruct...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BioMed Central
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3913946/ https://ncbi.nlm.nih.gov/pubmed/24451478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2049-3002-2-2 |
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