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Isoform-specific Binding of Selenoprotein P to the β-Propeller Domain of Apolipoprotein E Receptor 2 Mediates Selenium Supply

Sepp1 supplies selenium to tissues via receptor-mediated endocytosis. Mice, rats, and humans have 10 selenocysteines in Sepp1, which are incorporated via recoding of the stop codon, UGA. Four isoforms of rat Sepp1 have been identified, including full-length Sepp1 and three others, which terminate at...

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Hlavní autoři: Kurokawa, Suguru, Bellinger, Frederick P., Hill, Kristina E., Burk, Raymond F., Berry, Marla J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979378/
https://ncbi.nlm.nih.gov/pubmed/24532792
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.549014
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