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Acute and chronically increased immunoreactivity to phosphorylation-independent but not pathological TDP-43 after a single traumatic brain injury in humans

The pathologic phosphorylation and sub-cellular translocation of neuronal transactive response-DNA binding protein (TDP-43) was identified as the major disease protein in frontotemporal lobar degeneration (FTLD) with ubiquitinated inclusions, now termed FTLD-TDP, and amyotrophic lateral sclerosis (A...

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Detalhes bibliográficos
Main Authors: Johnson, Victoria E., Stewart, William, Trojanowski, John Q., Smith, Douglas H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3979333/
https://ncbi.nlm.nih.gov/pubmed/22101322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-011-0909-9
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