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An efficient and practical radiosynthesis of [(11)C]temozolomide
[Image: see text] Temozolomide (TMZ) is a prodrug for an alkylating agent used for the treatment of malignant brain tumors. A positron emitting version, [(11)C]TMZ, has been utilized to help elucidate the mechanism and biodistribution of TMZ. Challenges in [(11)C]TMZ synthesis and reformulation make...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3979304/ https://ncbi.nlm.nih.gov/pubmed/23151019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol302791x |
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