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Runx2 activates PI3K/Akt signaling via mTORC2 regulation in invasive breast cancer cells
INTRODUCTION: The Runt-related transcription factor Runx2 is critical for skeletal development but is also aberrantly expressed in breast cancers, and promotes cell growth and invasion. A de-regulated serine/threonine kinase Akt signaling pathway is implicated in mammary carcinogenesis and cell surv...
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| Format: | Artigo |
| Sprache: | Inglês |
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BioMed Central
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3979058/ https://ncbi.nlm.nih.gov/pubmed/24479521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3611 |
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