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Degradation of neutrophil extracellular traps co-varies with disease activity in patients with systemic lupus erythematosus
INTRODUCTION: The ability to degrade neutrophil extracellular traps (NETs) is reduced in a subset of patients with systemic lupus erythematosus (SLE). NETs consist of chromatin covered with antimicrobial enzymes and are normally degraded by DNase-I, an enzyme which is known to have reduced activity...
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| Autores principales: | , , , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
BioMed Central
2013
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3978901/ https://ncbi.nlm.nih.gov/pubmed/23945056 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4264 |
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