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Degradation of neutrophil extracellular traps co-varies with disease activity in patients with systemic lupus erythematosus

INTRODUCTION: The ability to degrade neutrophil extracellular traps (NETs) is reduced in a subset of patients with systemic lupus erythematosus (SLE). NETs consist of chromatin covered with antimicrobial enzymes and are normally degraded by DNase-I, an enzyme which is known to have reduced activity...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Leffler, Jonatan, Gullstrand, Birgitta, Jönsen, Andreas, Nilsson, Jan-Åke, Martin, Myriam, Blom, Anna M, Bengtsson, Anders A
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978901/
https://ncbi.nlm.nih.gov/pubmed/23945056
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4264
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