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A subset of patients with systemic lupus erythematosus fails to degrade DNA from multiple clinically relevant sources

INTRODUCTION: Patients with systemic lupus erythematosus (SLE) have a decreased ability to clear cell remnants and multiple deficiencies in the ability to degrade cellular chromatin have been linked to the disease. Since the discovery of neutrophil extracellular traps (NETs), a renewed interest has...

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Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Leffler, Jonatan, Ciacma, Katarzyna, Gullstrand, Birgitta, Bengtsson, Anders A., Martin, Myriam, Blom, Anna M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4535789/
https://ncbi.nlm.nih.gov/pubmed/26268365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0726-y
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