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Common breast cancer risk variants in the post-COGS era: a comprehensive review

Breast cancer has a strong heritable component, with approximately 15% of cases exhibiting a family history of the disease. Mutations in genes such as BRCA1, BRCA2 and TP53 lead to autosomal dominant inherited cancer susceptibility and confer a high lifetime risk of breast cancers. Identification of...

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Detalhes bibliográficos
Main Authors: Maxwell, Kara N, Nathanson, Katherine L
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978855/
https://ncbi.nlm.nih.gov/pubmed/24359602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3591
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