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Common breast cancer risk variants in the post-COGS era: a comprehensive review
Breast cancer has a strong heritable component, with approximately 15% of cases exhibiting a family history of the disease. Mutations in genes such as BRCA1, BRCA2 and TP53 lead to autosomal dominant inherited cancer susceptibility and confer a high lifetime risk of breast cancers. Identification of...
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Formato: | Artigo |
Idioma: | Inglês |
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BioMed Central
2013
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3978855/ https://ncbi.nlm.nih.gov/pubmed/24359602 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3591 |
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