Comprehensive analysis of common mitochondrial DNA variants and colorectal cancer risk

Several lines of evidence implicate mitochondrial dysfunction in the development of cancer. To test the hypothesis that common mtDNA variation influences the risk of colorectal cancer (CRC), we genotyped 132 tagging mtDNA variants in a sample of 2854 CRC cases and 2822 controls. The variants examine...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Webb, E, Broderick, P, Chandler, I, Lubbe, S, Penegar, S, Tomlinson, I P M, Houlston, R S
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2008
Pynciau:
Genetics and Genomics
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2607223/
https://ncbi.nlm.nih.gov/pubmed/19050702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6604805
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