Obesity enhances nongenomic estrogen receptor crosstalk with the PI3K/Akt and MAPK pathways to promote in vitro measures of breast cancer progression

INTRODUCTION: Epidemiological and clinical studies indicate that obesity is associated with a worse postmenopausal breast cancer prognosis and an increased risk of endocrine therapy resistance. However, the mechanisms mediating these effects remain poorly understood. Here we investigate the molecula...

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Bibliografske podrobnosti
Main Authors: Bowers, Laura W, Cavazos, David A, Maximo, Ilane XF, Brenner, Andrew J, Hursting, Stephen D, deGraffenried, Linda A
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978844/
https://ncbi.nlm.nih.gov/pubmed/23880059
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3453
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