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Obesity Suppresses Estrogen Receptor Beta Expression in Breast Cancer Cells via a HER2-Mediated Pathway

Obesity is associated with a worse breast cancer prognosis, while greater breast tumor estrogen receptor beta (ERβ) expression is correlated with improved therapy response and survival. The objective of this study was to determine the impact of obesity on breast cancer cell ERβ expression, which is...

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Pubblicato in:PLoS One
Autori principali: Bowers, Laura W., Wiese, Megan, Brenner, Andrew J., Rossi, Emily L., Tekmal, Rajeshwar R., Hursting, Stephen D., deGraffenried, Linda A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4692402/
https://ncbi.nlm.nih.gov/pubmed/26709918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0145452
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