The PI3K/Akt Pathway Mediates the Nongenomic Cardioprotective Effects of Estrogen Following Trauma-hemorrhage

OBJECTIVE: To determine whether the nongenomic actions of E2 have any beneficial effect on cardiac function following trauma-hemorrhage and whether those effects are mediated via the PI3K/Akt pathway. SUMMARY BACKGROUND DATA: Since studies suggest that both genomic and nongenomic pathways are involv...

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Main Authors: Yu, Huang-Ping, Hsieh, Ya-Ching, Suzuki, Takao, Choudhry, Mashkoor A., Schwacha, Martin G., Bland, Kirby I., Chaudry, Irshad H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1876963/
https://ncbi.nlm.nih.gov/pubmed/17522524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/01.sla.0000254417.15591.88
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