Intranasal Delivery of Mesenchymal Stem Cells Significantly Extends Survival of Irradiated Mice with Experimental Brain Tumors

Treatment options of glioblastoma multiforme are limited due to the blood–brain barrier (BBB). In this study, we investigated the utility of intranasal (IN) delivery as a means of transporting stem cell–based antiglioma therapeutics. We hypothesized that mesenchymal stem cells (MSCs) delivered via n...

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Detalhes bibliográficos
Main Authors: Balyasnikova, Irina V, Prasol, Melanie S, Ferguson, Sherise D, Han, Yu, Ahmed, Atique U, Gutova, Margarita, Tobias, Alex L, Mustafi, Devkumar, Rincón, Esther, Zhang, Lingjiao, Aboody, Karen S, Lesniak, Maciej S
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978787/
https://ncbi.nlm.nih.gov/pubmed/24002694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2013.199
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