ET-05 INTRANASAL DELIVERY OF NEURAL STEM CELLS LOADED WITH ONCOLYTIC ADENOVIRUS EXTENDS SURVIVAL OF MICE WITH INTRACRANIAL GLIOMA

Glioblastoma multiforme (GBM), the most common adult primary brain tumor, is in need of better and effective therapeutic options. In this study, we hypothesized that neural stem cells (NSCs) loaded with CRAd-S-pK7 oncolytic adenovirus (OV) can be successfully delivered via nasal application (IN) and...

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Main Authors: Balyasnikova, Irina, Dey, Mahua, Tobias, Alex, Kanojia, Deepak, Lee, Gina, Han, Yu, Zhang, Lingjiao, Ahmed, Atique, Aboody, Karen, Lesniak, Maciej
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4218148/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/nou255.5
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