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Mesenchymal Stem Cells Modified with a Single-Chain Antibody against EGFRvIII Successfully Inhibit the Growth of Human Xenograft Malignant Glioma
BACKGROUND: Glioblastoma multiforme is the most lethal brain tumor with limited therapeutic options. Antigens expressed on the surface of malignant cells are potential targets for antibody-mediated gene/drug delivery. PRINCIPAL FINDINGS: In this study, we investigated the ability of genetically modi...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Public Library of Science
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2841188/ https://ncbi.nlm.nih.gov/pubmed/20305783 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009750 |
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