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Therapeutic Effect of Neural Stem Cells Expressing TRAIL and Bortezomib in Mice with Glioma Xenografts

Treatment of glioblastoma remains a challenge in neuro-oncology. We investigated if treatment with neural stem cells engineered to express membrane-bound TRAIL (NSCs-mTRAIL) alone or in combination with proteasome inhibitors is a feasible therapeutic approach for experimental glioma. Glioma cells sh...

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Detalhes bibliográficos
Main Authors: Balyasnikova, Irina V., Ferguson, Sherise D., Han, Yu, Liu, Feifei, Lesniak, Maciej S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3159776/
https://ncbi.nlm.nih.gov/pubmed/21802840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2011.06.029
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