Transforming growth factor-β signalling controls human breast cancer metastasis in a zebrafish xenograft model

INTRODUCTION: The transforming growth factor beta (TGF-β) signalling pathway is known to control human breast cancer invasion and metastasis. We demonstrate that the zebrafish xenograft assay is a robust and dependable animal model for examining the role of pharmacological modulators and genetic per...

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Main Authors: Drabsch, Yvette, He, Shuning, Zhang, Long, Snaar-Jagalska, B Ewa, ten Dijke, Peter
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978640/
https://ncbi.nlm.nih.gov/pubmed/24196484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3573
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