Influence of the ABCG2 gout risk 141 K allele on urate metabolism during a fructose challenge

INTRODUCTION: Both genetic variation in ATP-binding cassette sub-family G member 2 (ABCG2) and intake of fructose-containing beverages are major risk factors for hyperuricemia and gout. This study aimed to test the hypothesis that the ABCG2 gout risk allele 141 K promotes the hyperuricaemic response...

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Autors principals: Dalbeth, Nicola, House, Meaghan E, Gamble, Gregory D, Pool, Bregina, Horne, Anne, Purvis, Lauren, Stewart, Angela, Merriman, Marilyn, Cadzow, Murray, Phipps-Green, Amanda, Merriman, Tony R
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2014
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978630/
https://ncbi.nlm.nih.gov/pubmed/24476385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4463
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