Serum nitrated nucleosome levels in patients with systemic lupus erythematosus: a retrospective longitudinal cohort study

INTRODUCTION: Circulating nucleosomes released from apoptotic cells are important in the pathogenesis of systemic lupus erythematosus (SLE). Both nucleosomes and anti-nucleosome antibodies are deposited in inflamed tissues in patients with SLE. Active inflammation promotes nitration of tyrosine resi...

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Bibliographic Details
Main Authors: Croca, Sara, Bassett, Paul, Pericleous, Charis, Alber, Karim Fouad, Latchman, David, Isenberg, David, Giles, Ian, Rahman, Anisur, Ioannou, Yiannis
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978622/
https://ncbi.nlm.nih.gov/pubmed/24502558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4477
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