Persistence and selection of an expanded B-cell clone in the setting of rituximab therapy for Sjögren’s syndrome

INTRODUCTION: Subjects with primary Sjögren’s syndrome (SjS) have an increased risk of developing B-cell lymphoma and may harbor monoclonal B-cell expansions in the peripheral blood. Expanded B-cell clones could be pathogenic, and their persistence could exacerbate disease or predispose toward the d...

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Main Authors: Hershberg, Uri, Meng, Wenzhao, Zhang, Bochao, Haff, Nancy, St Clair, E William, Cohen, Philip L, McNair, Patrice D, Li, Ling, Levesque, Marc C, Luning Prak, Eline T
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2014
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978607/
https://ncbi.nlm.nih.gov/pubmed/24517398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4481
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