A simple consensus approach improves somatic mutation prediction accuracy

Differentiating true somatic mutations from artifacts in massively parallel sequencing data is an immense challenge. To develop methods for optimal somatic mutation detection and to identify factors influencing somatic mutation prediction accuracy, we validated predictions from three somatic mutatio...

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Bibliografiske detaljer
Main Authors: Goode, David L, Hunter, Sally M, Doyle, Maria A, Ma, Tao, Rowley, Simone M, Choong, David, Ryland, Georgina L, Campbell, Ian G
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2013
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Method
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3978449/
https://ncbi.nlm.nih.gov/pubmed/24073752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm494
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