Analysis of the Mitogen-activated protein kinase kinase 4 (MAP2K4) tumor suppressor gene in ovarian cancer

BACKGROUND: MAP2K4 is a putative tumor and metastasis suppressor gene frequently found to be deleted in various cancer types. We aimed to conduct a comprehensive analysis of this gene to assess its involvement in ovarian cancer. METHODS: We screened for mutations in MAP2K4 using High Resolution Melt...

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Bibliographic Details
Main Authors: Davis, Sally J, Choong, David YH, Ramakrishna, Manasa, Ryland, Georgina L, Campbell, Ian G, Gorringe, Kylie L
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3115913/
https://ncbi.nlm.nih.gov/pubmed/21575258
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-173
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